Tottenham Hotspur fixture list for the 2022/23 season
All fixtures are subject to potential change due to European competitions and TV selection.
| Sunday, 28 August 2022 | ||
| Nottingham Forest | 0-2 | Tottenham Hotspur |
| Wednesday, 31 August 2022 | ||
| West Ham United | 1-1 | Tottenham Hotspur |
| Saturday, 3 September 2022 | ||
| Tottenham Hotspur | 2-1 | Fulham |
| Saturday, 10 September 2022 | ||
| Manchester City | 4-2 | Tottenham Hotspur |
| Saturday, 17 September 2022 | ||
| Tottenham Hotspur | 6-2 | Leicester City |
| Saturday, 1 October 2022 | ||
| Arsenal | 3-1 | Tottenham Hotspur |
| Saturday, 8 October 2022 | ||
| Brighton & Hove Albion | 0-1 | Tottenham Hotspur |
| Saturday, 15 October 2022 | ||
| Tottenham Hotspur | 2-0 | Everton |
| Wednesday, 19 October 2022 | ||
| Manchester United | 2-0 | Tottenham Hotspur |
| Saturday, 22 October 2022 | ||
| Tottenham Hotspur | 1-2 | Newcastle United |
| Saturday, 29 October 2022 | ||
| Bournemouth | 2-3 | Tottenham Hotspur |
| Saturday, 5 November 2022 | ||
| Tottenham Hotspur | 1-2 | Liverpool |
| Saturday, 12 November 2022 | ||
| Tottenham Hotspur | 4-3 | Leeds United |
| Monday, 26 December 2022 | ||
| Brentford | 2-2 | Tottenham Hotspur |
| Saturday, 31 December 2022 | ||
| Tottenham Hotspur | 0-2 | Aston Villa |
| Monday, 2 January 2023 | ||
| Crystal Palace | 0-4 | Tottenham Hotspur |
| Saturday, 14 January 2023 | ||
| Tottenham Hotspur | 0-2 | Arsenal |
| Saturday, 21 January 2023 | ||
| Fulham | 0-1 | Tottenham Hotspur |
| Sunday, 5 February 2023 | ||
| Tottenham Hotspur | 22:00 | Manchester City |
| Saturday, 11 February 2023 | ||
| Leicester City | 20:30 | Tottenham Hotspur |
| Wednesday, 15 February 2023 | ||
| AC Milan | 01:30 | Tottenham Hotspur |
| Sunday, 19 February 2023 | ||
| Tottenham Hotspur | 22:00 | West Ham United |
| Sunday, 26 February 2023 | ||
| Tottenham Hotspur | 19:00 | Chelsea |
| Saturday, 4 March 2023 | ||
| Wolverhampton Wanderers | 20:30 | Tottenham Hotspur |
| Thursday, 9 March 2023 | ||
| Tottenham Hotspur | 01:30 | AC Milan |
| Saturday, 11 March 2023 | ||
| Tottenham Hotspur | 20:30 | Nottingham Forest |
| Saturday, 18 March 2023 | ||
| Southampton | 20:30 | Tottenham Hotspur |
| Saturday, 1 April 2023 | ||
| Everton | 19:30 | Tottenham Hotspur |
| Saturday, 8 April 2023 | ||
| Tottenham Hotspur | 19:30 | Brighton & Hove Albion |
| Saturday, 15 April 2022 | ||
| Tottenham Hotspur | 19:30 | Bournemouth |
| Saturday, 22 April 2023 | ||
| Newcastle United | 19:30 | Tottenham Hotspur |
| Wednesday, 26 April 2023 | ||
| Tottenham Hotspur | 00:15 | Manchester United |
| Saturday, 29 April 2023 | ||
| Liverpool | 19:30 | Tottenham Hotspur |
| Saturday, 6 May 2023 | ||
| Tottenham Hotspur | 19:30 | Crystal Palace |
| Saturday, 13 May 2023 | ||
| Aston Villa | 19:30 | Tottenham Hotspur |
| Saturday, 20 May 2023 | ||
| Tottenham Hotspur | 19:30 | Brentford |
| Saturday, 28 May 2023 | ||
| Leeds United | 19:30 | Tottenham Hotspur |
